Biodegradation of glyceryl trinitrate by Penicillium corylophilum Dierckx

Activation of trigeminovascular neurons by glyceryl trinitrate.

The effect of intra-carotid arterial infusions of glyceryl trinitrate (GTN), a substance known to precipitate headache, including migraine, upon the spontaneous activity of trigeminal neurons with craniovascular input was studied in cats. Second-order craniovascular neurons which received sensory input from the superior sagittal sinus were recorded in the trigeminal nucleus caudalis. Infusions ...

Comparison with glyceryl trinitrate

The coronary haemodynamic effects of nifedipine and glyceryl trinitrate were compared in 22 patients undergoing investigations for suspected coronary artery disease. Myocardial blood flow was estimated by the coronary sinus thermodilution technique. In sinus rhythm nifedipine increased mean coronary sinus flow from 135 ml/min to 152 m/min, and reduced arterio-coronary sinus oxygen difference fr...

Glyceryl trinitrate before coronary angiography.

Patients' knowledge of sublingual glyceryl trinitrate.

of stones from the gall bladder.3 There are several clinical implications. The long contiguous course of the cystic duct and common hepatic duct could explain why surgeons sometimes inadvertently leave a long remnant of cystic duct, which is reputedly a cause of the postcholecystectomy syndrome.4 Furthermore, the migration of stones from the gall bladder into the contiguous segment may explain ...

Inhibition of platelet aggregation by transdermal glyceryl trinitrate.

OBJECTIVE To determine the optimum conditions for the demonstration of an antiplatelet effect of nitric oxide and to use these conditions to elucidate the effects of a transdermal glyceryl trinitrate patch on platelet aggregation in normal volunteers. METHODS An open prospective crossover study. The effects of nitric oxide on platelet aggregation in whole blood and platelet rich plasma as sti...